Als der Biologe Derrick Rossi vor mehr als zehn Jahren Kenneth Chien vorschlug, mit ihm ein Biotech-Unternehmen zu gründen, dachte der Arzt und Wissenschaftler darüber nach, wie etwaige Fortschritte auf sein Fachgebiet, das Herz, angewendet werden könnten. Moderna wurde 2010 auf der Grundlage von Rossis Entdeckung gegründet, menschliche Hautzellen – Fibroblasten – mithilfe synthetischer mRNA in Zellen umzuprogrammieren, die mit embryonalen Stammzellen identisch sind. Doch erst im Labor von Chien, einem Experten für molekulare Kardiologie, wurde die Wirksamkeit der mRNA-basierten Technologie getestet.
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